Company Profile: Blue Marble Energy

A couple of months ago I met the founders of Blue Marble Energy at a party for the Apollo Alliance.  Following up, I sat down with the CEO, Kelly Ogilvie, to learn about Blue Marble, which is the only "algal biofuel" company I have come across that really makes sense to me.  (While at the party, I also chatted with Congressman Jay Inslee for quite a while.  Smart fellow.  Anyone interested in energy policy should have a look at his book, Apollo's Fire: Igniting America's Clean Energy Economy.)

Full disclosure: Blue Marble and Biodesic may begin collaborating soon, so I am not an entirely disinterested observer.

Blue Marble Energy is built around the idea of "recombining" existing biological processes to turn biomass into valuable products.  From the website: "[Blue Marble Energy] uses anaerobic digestion to generate natural gas and other valuable bio-chemical streams."  The company is distinguished from its competitors by its focus on using micro- and macro-algae harvested from natural blooms, including those caused or enhanced by human activity, as feedstock for artificial digestion systems modeled on those of ruminants.  Blue Marble combines different sets of microbes in a series of bioreactors to produce particular products. 

In other words, Blue Marble is using industrialized, artificial cow stomachs to produce fuel and industrial products.

The company's general strategy is to first digest cellulose into synthesis gas (carbon dioxide and hydrogen) using one set of organisms, and then feed the synthesis gas to organisms that generate methane or higher margin chemicals and solvents.  The company expects to produce 200-300 cubic meters of methane per wet ton of algal feedstock.  While biofuels are an obvious target for technology like this, the company also recognizes that fuels are a low margin commodity business.  Thus Blue Marble also plans to produce higher margin industrial products, including solvents such as various esters that sell for $400-800 per gallon.

While other companies are attempting to directly produce fuels from cultured algae, Blue Marble believes these efforts will be hampered by growth limitations in most circumstances.  Biofuel production from algal lipids synthesized during photosynthetic growth requires conditions that cause metabolic stress, resulting in lipid production, but that also limit total biomass yield to ~2-5 grams per liter.  In contrast, Blue Marble "respects the complex ecology", in the words of Mr. Ogilvie, and relies on photoheterotrophic growth of whatever happens to grow in open water.

Blue Marble has already obtained contracts to clean up algal growth caused by human activity around Puget Sound.  The company typically harvests ~100 grams per liter from these "natural" algal blooms.  Future plans include expanding these clean up operations around the U.S. and overseas, and growing algae in wastewater, which would provide a high-energy resource base for both closed and open system growth.  In principle, because the technology is modeled on ruminant digestion, many different sources of biomass should be usable as feedstock.  Experience thus far indicates that feedstocks with higher cellulose content result in higher yield production of fuels and solvents.

Compared with other algal biofuel companies, Blue Marble does not presently require high capital physical infrastructure for growing algae.  However, the company will rely on marine harvesting operations, which bring along a different set of complexities and costs.  I wonder if the company might be best served if it outsourced harvesting activities and focused on the core technology of turning biomass into higher value products.

While the Blue Marble is not now genetically modifying their production organisms, this will likely prove a beneficial move in the long term.  Tailoring both the production ecosystem and the metabolisms of component organisms will certainly be a goal of competitors, as is already the case with companies spanning a wide range of developmental stages, including DuPont, Amyris, and Synthetic Genomics.  Yet whereas modified production organisms grown in closed vats are likely to face little opposition on any front, genetically modified feedstocks grown in open waters are another matter.  For the time being, Blue Marble has an advantage over plant genomics companies because in the company's plans to use unmodified biomass as feedstock, whether algae or grasses, it will avoid many regulatory and market risks facing companies that hope to grow genetically modified feedstocks in large volumes. 

They have a long way to go, but in my judgement Blue Marble appears to have a better grasp than most on the economic and technical challenges of using algae as feedstock for fuels and materials.

Further reading:

"It came from the West Seattle swamp - to fill your tank", Eric Engleman, Puget Sound Business Journal, August 8, 2008

"Swamp fever", Peter Huck, The Guardian, January 9 2008
http://www.guardian.co.uk/environment/2008/jan/09/biofuels.alternativeenergy

"New wave in energy: Turning algae into oil", Erica Gies, International Herald Tribune, June 29, 2008

Methane Time Bomb Update

Following on its coverage of an expedition to Russia's northern coast that found methane deposits leaking through melting permafrost into the water and atmosphere, The Independent has news that a British expedition to the seas off the coast of Norway has discovered "hundreds of methane plumes".  From the article:

Yesterday, researchers on board the British research ship the James Clark Rosssaid they had counted about 250 methane plumes bubbling from the seabed in an area of about 30 square miles in water less than 400 metres (1,300 feet) deep off the west coast of Svalbard. They have also discovered a set of deeper plumes at depths of about 1,200 metres at a second site near by.

The story notes that "It is likely that methane emissions off Svalbard have been continuous for about 15,000 years – since the last ice age."  I think it is fascinating that these plumes have only just been discovered.  This means the methane budget of the atmosphere is probably still quite poorly understood, even as it is clear new sources of methane are opening due to climate change.

Cleaning out some bookmarks

In no particular order of importance:

  • Metbolix has announced it has modified switchgrass to produce PHA.  The "Mirel history" page on the website suggests there are 7 enzymes in the pathway.  An independent Life Cycle Analysis of Mirel, "Conducted by Dr. Bruce Dale, professor of Chemical Engineering at Michigan State University, determined that production of Mirel reduces the use of nonrenewable energy by more than 95% and provides a 200% reduction in greenhouse gases (GHG) compared to production of conventional petroleum-based plastics. concluded."  (PDF Press release)
  • Here is an essay from Jeremy Haft (WSJ via Huffington Post) that opines the US has a permanent competitive edge over China.  Really?
  • A couple of posts from Wired on saving our economy with a cleantech/greentech bubble.  'Cuz bubbles really keep us afloat.  Until they pop.  And we write $700 billion dollar checks.  Right... 

"Methane time bomb"

The Independent carried a story on Tuesday that should alarm anyone interested in climate change (anthropogenic or otherwise).

"Exclusive: The methane time bomb", by Steve Connor, describes a just concluded methane sampling expedition along "the entire length of Russia's northern coast".  Interested readers should just follow the link to get the whole story.  To summarize: warming waters are releasing so much methane from previously trapped deposits that in some areas the seas are literally foaming as gas bubbles up from below.  Previous sampling cruises in the area have detected increasing concentrations of dissolved methane in water, but apparently methane deposits are escaping at an increasing rate.  Here is a good number from the article to keep in mind: the arctic region as a whole has warmed 4 degrees C in the last decade.

Since the release is caused by melting permafrost, there isn't much we can do to stop it.  So, given that methane is a much more powerful greenhouse gas than carbon dioxide, we might want to give some thought to attempting a fix.

Jamais Cascio has been following this threat for quite a while, and extends here his thoughts on dealing with atmospheric methane using geo-engineering using bio-engineered microbes.

Jamais writes:

The most conservative estimates I've seen start at around 70 billion metric tons of methane -- the equivalent in greenhouse terms to 1.6 trillion metric tons of CO2. As a point of comparison, the total annual greenhouse footprint in the US is about 7 billion tons; globally, the annual footprint is about 30 billion tons.

If this methane leak continues to increase, we may be facing a disastrous result that no amount of renewable energy, vegetarianism, and bicycling will help. This is one scenario in which the deployment of geoengineering is over-determined, probably needing to remain in place for quite a while as we try to remove the methane (or, at worst, wait for it to cycle out naturally over the course of a decade or so). It's also a scenario that might require large-scale use of bioengineering.

That would be, to put it lightly, an extremely hard project.  And we are nowhere near ready to start.  Happy Thursday.

"Coskata Due Diligence"

Oliver Morton at Nature pointed me to a bunch of excellent posts on Coskata by Robert Rapier at R-Squared.  Recall that Coskata wants to gasify cellulose and feed the resulting synthesis gas to bugs that make ethanol.  Here are Rapier's "Coskata"-tagged posts.

Among other points, Rapier makes some nice back of the envelope estimates of the technical and economic feasibility of Coskata's process.  In short, Coskata's claims appear to be consistent with the laws of thermodynamics, but perhaps not so much with the law of supply and demand, and their logistics challenges might border on being inconsistent with the consevation of matter.

Basically, it all, err, "boils down" to the fact that Coskata is probably going to get tripped up by their focus on ethanol and the consequent energy cost of separating ethanol from water.  Even if you have a nifty process for turning cellulose into ethanol, it takes a large fraction of the energy in the cellulose to purify the ethanol.  And it really doesn't matter whether you distill or use a membrane -- the entropy of mixing still hoses you even if you somehow escape the specific heat of water and its enthalpy of vaporization.

Now if you hacked the metabolic pathway that consumes synthesis gas so that the bug made something more interesting like butanol, or a gasoline analog, that either had lower miscibility or even phase separated, that would really be something because it would minimize the energy cost of purification.

Great work, Mr. Rapier.  And many thanks, Oliver.

More on China's Economy, Food Production, and Food Demand

Over the next two decades the Panda may begin to feel peckish. A hard look at China's food production and resource availability suggests more difficult times ahead. And this is just one potential problem. Throughout my travels and reading over the past 5 years, I have noticed that people with lots of experience on the ground in China question whether the current pace of development is sustainable.

The upshot of all this may be that the easy gains have been made. In the years to come, China will be faced with extremely hard choices about how to simultaneously maintain economic growth, clean up its environment, and feed its population, particularly when it appears that most of the expected increase in food demand due to rising incomes has yet to be realized. So, following up on last week's post about The Future of China's Economy, here are a few more thoughts that frame future potential stumbling blocks.

Running Out of Cheap Labor, and Coming Home for L.A.'s "Clean" Air

John Pomfret, formerly the Beijing Bureau Chief for the Washington Post, definitely has a lot of experience in country. In "A Long Wait at the Gate to Greatness", he asks, "Is China really going to be another superpower?"

His short answer is, "I doubt it." In more depth:

It's not that I'm a China-basher, like those who predict its collapse because they despise its system and assume that it will go the way of the Soviet Union. I first went to China in 1980 as a student, and I've followed its remarkable transformation over the past 28 years. I met my wife there and call it a second home. I'm hardly expecting China to implode. But its dream of dominating the century isn't going to become a reality anytime soon.

Too many constraints are built into the country's social, economic and political systems. For four big reasons -- dire demographics, an overrated economy, an environment under siege and an ideology that doesn't travel well -- China is more likely to remain the muscle-bound adolescent of the international system than to become the master of the world.

Pomfret goes through the same sort of list of potential stumbles that I compiled for last week's post, and adds a few more. He notes that that population control policy has produced an inverted population pyramid, which requires a smaller, young population cohort to support a larger, older cohort as the latter leave the workforce. This while life expectancy has more than doubled in the last fifty years. Thus the expectation is that the workforce will shrink over the coming decades, labor costs will rise, and more of that labor will be put toward supporting non-working elders.

Pomfret also observes that:

One important nuance we keep forgetting is the sheer size of China's population: about 1.3 billion, more than four times that of the United States. China should have a big economy. But on a per capita basis, the country isn't a dragon; it's a medium-size lizard, sitting in 109th place on the International Monetary Fund's World Economic Outlook Database, squarely between Swaziland and Morocco. China's economy is large, but its average living standard is low, and it will stay that way for a very long time, even assuming that the economy continues to grow at impressive rates.

Unlike many observers, he doesn't discount the potential drag on economic growth from pollution, leading off with a personal anecdote:

When my family and I left China in 2004, we moved to Los Angeles, the smog capital of the United States. No sooner had we set foot in southern California than my son's asthma attacks and chronic chest infections -- so worryingly frequent in Beijing -- stopped. When people asked me why we'd moved to L.A., I started joking, "For the air."

Pomfret is perplexed about why Westerners seem to be ignoring pollution's ~10% hit to the Chinese GDP: "Somehow, though, the effect this calamity is having on China's rise doesn't quite register in the West." As I discussed in the earlier post, this shortsightedness confuses me, too, particularly when you combine the effects of pollution with the demands on domestic water and land to provide food for a hungry population.

Missing Food Demand

In a report last year from the Economic Research Service of the USDA, Fred Gale and Kuo Huang suggest that China may face increasing difficulties in meeting domestic food demand. I find their argument quite compelling and will later state it even more firmly than they do.

Gale and Huang observe that growth in food demand has, unexpectedly, not kept pace with overall economic growth. Here is the conundrum: "Given the responsiveness of food demand to income growth, China's rapid growth of 9-10 percent per year suggests that its demand for food is growing faster than its production capacity. ...How is it that China's surging income growth has not pushed its demand for food beyond its domestic production capacity?"

The main factor the authors identify is that while a small, wealthy fractionof the population now evidently has enough to eat, and thus spends additional income on quality rather than quantity, a large majority of consumers have yet to fill their bellies.

The underlying cause for lagging food demand is not surprising once you think about it. Because economic benefits, in particular income gains, disproportionately go those with already high incomes, and because those with high incomes tend to spend on quality rather than quantity, the total volume of food consumed by the Chinese population has risen only slowly. The authors note that:

...Expenditures by the top tier of households--China's emerging class of professionals and entrepreneurs -- have grown at double-digit rates. Food expenditures were nearly stagnant for the bottom 20 percent of urban households. Food expenditures by rural households grew 2.6 percent annually.

...Income growth for low-income urban and rural households--the majority of China's households--was well below GDP growth. ...Average income for the lowest decile of urban households actually declined slightly between 2000 and 2003.

This suggests to Gale and Huang that, "Food consumption and income growth patterns may explain how China has been able to remain self-sufficient in most food items." The authors stop their argument here, but I think they could go further.

The Still-Hungry ~1 Billion

The lag between GDP growth and food consumption has important implications for future increases in food demand.

Based on the statistics compiled by Gale and Huang, it looks to me like more than 90% of the Chinese population has a per capita annual income below 10,000 Yuan. This is an interesting figure for considering future food demand because Gale and Huang also demonstrate that pork consumption in China continues to rise as a function of income until about 10,000 Yuan. Poultry and seafood consumption also rise strongly as a function of income, but notably don't saturate like pork at 10,000 Yuan. More meat consumption requires more grain and more water to raise the animals (see a previous post, "China and Future Resource Demands").

Here is where I think the argument could be made more forcefully.  As best I can make out, what all the above means is that most of the increase in food demand we might expect from rising incomes in China has yet to be realized; more than 80% of the population is, "Still at income levels where they demand increased quantities of many foods as their income rises."

So where is China going to get all this food? One answer is imports, another is to go offshore to buy or rent farmland (see the "China and Future Resource Demands" post), and yet another is to push domestic production. But the latter may be difficult.

"Who Will China Feed?"

This is the question asked by Fred Gale and Bryan Lohmar in an essay in Amber Waves, the USDA magazine. They elaborate their surprise at China's ability to feed its population: "While China has emerged as the world's leading importer of soybeans, vegetable oil, cotton, wool, rubber, and animal hides, it has been surprisingly successful at meeting the basic food needs of its population of more than 1.3 billion people, and it has stepped up as a major food exporter."  (They make no mention of the income inequality and consequent food spending gap explored above.)

Given the pace of growth and limited resources, they ask, "How long can China sustain this momentum?"

China imports only small amounts of premium-grade rice, minor amounts of wheat in most years, and no corn. China has maintained agricultural self-sufficiency in grains as it carries out the world's largest and fastest urbanization and industrialization. Economic development is increasing competition for scarce resources in China, but growing incomes are allowing most consumers to increase consumption of fruit, vegetables, and livestock products.

China has become a significant food exporter by ramping up production in many sectors and gaining world market share. Indeed, China has been a net food exporter for most of the last three decades. China dominates world markets in a variety of products areas, including garlic, apples, apple juice, mandarin oranges, farm-raised fish and shrimp, and vegetables. At times, it seems that China has suspended the law of scarcity by boosting production in many sectors and selling at low prices without having to sacrifice production in other sectors.

One way to look at this is that China is exporting high value "food products", not staples that the majority of Chinese themselves consume. This strategy contributes to the trade surplus, but the use of land to grow crops for export must clearly be balanced with domestic demand for staples. This balance also points to the fact there is some room for moving crop land now used for exports back into production to satisfy domestic demand.

Here are two key paragraphs on how China has increased its food production yields:

Investments in research and development raised the quality of inputs and the efficiency of their use over the past two decades. Research into improved varieties and quality of seeds surged after the late 1970s. By the turn of the century, China had more agricultural researchers than any other country, and a larger budget for public sector agricultural research than any developing country. Fertilizer quality in China also has improved over the past two decades, as farmers move away from applying pure nitrogen fertilizer to applying more nitrogen-phosphorous- potassium blends. China has been importing breeding animals--which are often crossed with domestic breeds--to improve efficiency of weight gain, improve disease resistance, and raise milk output. The government has offered subsidies to farmers for dairy herd improvement for several years.

China today is the world's largest agricultural producer and consumer. With an estimated 10 percent of world land resources and 6 percent of world water resources, China produces 30 percent of the world's rice, 20 percent of the world's corn, a fourth of the world's cotton, an estimated 37 percent of the world's fruit and vegetables, and half of the world's pork. For most products, China's world share of production is close to or exceeds its 20-percent share of world population. China, however, has exploited the means of coaxing food and fiber out of a limited natural resource base to the extent that additional gains will be more difficult than in the past.

Gale and Lohmar go on to discuss water and soil quality issues, fertilizer and pesticide use, and industrial pollution, while briefly addressing labor costs:

China has been able to maintain low-cost production in international agricultural markets largely because of low labor costs. Historically, Chinese farms have raised large amounts of output from small plots by using labor-intensive production strategies, such as growing multiple crops per year, intercropping, and growing vegetables in courtyards. But hundreds of millions of rural workers have found nonfarm employment over the last two decades. The flow of labor from rural areas enabled China's industry and cities to boom, while wage growth was relatively stagnant for much of the last two decades.

China's rapid economic expansion appears to have finally exhausted the pool of under-employed workers. Since 2003, wages have been rising at a double-digit pace. The dwindling pool of available rural workers is resulting in increased mechanization of harvesting and planting. Anecdotal evidence also suggests that intensive agricultural practices, like double-cropping, transplanting seedlings by hand, and small-scale hog production, have decreased due to labor shortages and high wages.

So, as John Pomfret suggested in his piece in the Washington Times Post (!), labor costs are already affecting food production. But the bigger issue is in trying to identify where, exactly, future gains in production are going to come from.  Rough estimates of the probable increase in demand give some context for the magnitude of the problem.

Returning to the correlation of meat consumption and income: It appears from FAO and USDA data that China is bound to eat more meat, especially pork, as incomes continue to rise.  Growing meat for human consumption creates a big lever in water and grain markets.  Producing a kilo of pork requires approximately three kilos of grain, and producing a kilo of beef requires about eight kilos of grain.  Based on the data in Gale and Huang, in appears that as income rises from 3000 to 10,000 Yuan, pork consumption increases by about 50%, to ~23 kg, which will require about 70 kg of grain.  This in addition to the ~30% increase in grain products (~6 kg) directly purchased by households as incomes rise over that range.  Fish and poultry demand about doubles, too, from ~8 to ~16 kg per capita, but estimating the additional grain consumption here is hard.  I'll hand wave and make a low-ball estimate that it will take only another 16 kg of grain to feed the the fish and poultry.

Adding this all together, that is an additional per capita  increase in grain demand of more than 90 kg.  Here is the kicker: that number appears to hold for at least 500 million people, perhaps as many as a billion.  That amounts to at least 45 million tonnes (metric!) of grain, perhaps as much as 90 million tonnes.  The Chinese population would then still be consuming only about 80% as much animal protein per capita as Europeans, and only a little over half as much as us gluttons in the U.S.

China produces about 500 million tonnes of grain per year (see the USDA ERS China Ag and Economic data page), so supplying increased meat demand with domestic grain supplies would require a (very rough) increase of between 10 and 20% in total yield.  That doesn't necessarily sound like much -- I actually expected the increase to be a larger percentage of current harvests -- and might be accomplished by breeding, genetic modification, and better farming practices.  But as detailed in my earlier posts, China is losing both arable land and usable water.  With only 7% of the globe's arable land to work with (ignoring losses to due climate change and prior poor farming practices), the country is going to have to work very hard indeed to squeeze more grain out of those limited resources.

That leaves imports, which means competing on the world commodity markets for food.  In combination with rising labor costs at home, all this points to rising domestic prices and rougher going for the Chinese economy.

"The Pickens Plan" for Wind Energy: Why Use Natural Gas for Cars?

Oilman T. Boone Pickens made a splash last week by announcing plans to build a wind farm with 4,000 megawatts worth of generating capacity.  The Pickens Plan calls the U.S. the Saudi Arabia of oil wind, and he notes that, "At current oil prices, we will send $700 billion dollars out of the country this year alone — that's four times the annual cost of the Iraq war."  His logic in making this investment is pretty straightforward:

Building wind facilities in the corridor that stretches from the Texas panhandle to North Dakota could produce 20% of the electricity for the United States at a cost of $1 trillion. It would take another $200 billion to build the capacity to transmit that energy to cities and towns.

That's a lot of money, but it's a one-time cost. And compared to the $700 billion we spend on foreign oil every year, it's a bargain.

Great -- the more energy we generate at home, the more we can invest in rebuilding the U.S. economy and infrastructure.  Somewhat less obvious is the logic of his suggestion that this electricity be used to free up natural gas now burned to provide ~20% of US electricity, and instead use that gas to power cars.

There are very few natural gas powered cars in this country, and it would take an enormous investment to either retrofit existing vehicles or replace a large fraction of the existing fleet in less time than the present ~13 year life cycle.  Moreover, burning natural gas in large turbines is way more efficient than burning it in small car engines, so it is actually better used to produce electricity for the grid.  It would seem to make more sense to just use the added electricity generation capacity from wind to directly offset petroleum use.

Why not just replace or retrofit the fleet with plug-in hybrids that substantially increase the efficiency of cars regardless of their fuel type?  Then you could be agnostic about the specific engine technology and fuel, but still know you could potentially double the mileage of any given vehicle by recharging from the electricity grid?  Here, for example, is a story at Wired News by Chuck Squatriglia in which Andy Grove, the CEO of Intel, calls for converting 10 million cars and trucks in the U.S. to plug in hybrids over the next four years.  The story quotes John Dabels, CEO of conversion start-up EV Power Systems, as saying his company can provide an $11,000 conversion kit that bolts onto the transmission of existing cars and trucks and delivers a 30-40% increase in liquid fuel efficiency.  Google has evidently been running a fleet of plug-in Priuses and Escapes with a 50% improvement over the standard hybrid.  These are early numbers.  Efficiencies are bound to increase as better batteries and electric motors enter the market.

Pair plug-in hybrids with microbial biofuel synthesis -- oh, alright, and even cellulosic ethanol -- and suddenly you get way more out of your feedstock and thereby reduce pressure on food prices.  Not that I am biased or anything.

The Future of China's Economy

It's hot and damp in southeastern China this time of year.  So reports a relative of mine working in the area who called to chat a few days ago.  He was suffering through another day without air conditioning, in the middle of yet another regional power outage due to a shortage of coal.  This occurrence is evidently not uncommon.  We hear a great deal in the U.S. about the unstoppable juggernaut of the Chinese economy, but sometimes I wonder if the Chinese aren't setting themselves up for a stumble or two.

(Update: For more on resource demands, see my subsequent post "More on China's Economy, Food Production, and Food Demand".)

Many of the signs point to inevitable economic superiority.  The Carnegie Endowment for International Peace released a report last week that projects China's economy will overtake that of the U.S. by 2035 (Yahoo News). "China's Economic Rise--Fact and Fiction", by Albert Keidel, concludes that China's economy is now dominated by internal growth rather than exports, and that China's economy will be twice that of the U.S. by 2050.  Keidel gives the nod to financial and bureaucratic tangles as the primary threats to growth, but does not appear particularly concerned about environmental damage and pollution. He argues that:

The record for several other East Asian economies argues that pollution is unlikely to undermine China's growth in the coming decades. In particular, Japan, South Korea, and Taiwan all passed through similar periods of serious pollution associated with rapid industrialization. In these cases, policy responses were also delayed but eventually reduced pollution levels that in some dimensions were worse than China's today.

Maybe so, but, depending on how you look at the numbers, the cost of pollution may be wiping out all of China's GDP growth.

(Update 25 July, 2008: Here is a video feed from Fora.tv of a panel discussion at the Carnegie Endowment for International Peace discussing the "Fact and Fiction" report.  I haven't watched the whole thing yet...)

Attempting to Account for the Costs of Pollution

For most of the last decade, China's government has downplayed the cost of environmental damage to the country's GDP.  However, according The Economist, in March of 2008, Pan Yue, a deputy minster at the State Environmental Protection Agency (SEPA), publicly estimated that environmental damage reduces GDP by as much as 13%.  As recently as May, 2006, the official estimate was only 3% of GDP for 2004, a tally contained in the first and only "green audit" of the economy.

The direct costs to human life are substantial, but official estimates are also variable.  A study by SEPA and The World Bank, published last year, "The Cost of Pollution in China", estimates that pollution is directly responsible for at least 750,000 deaths a year, while in a 2006 speech Mr. Pan stated that approximately 70% of China's two million annual cancer deaths were caused by pollution.

The disparity in these figures is evidently caused by political tension between different parts of the Chinese government.  Both the health findings and the future of the "green GDP audit" were evidently compromised by political infighting between state scientists, regional leaders, and officials in other ministriesThe New York Times reported that:

The official explanation was that the science behind the green index was immature. Wang Jinnan, the leading academic researcher on the Green G.D.P. team, said provincial leaders killed the project. "Officials do not like to be lined up and told how they are not meeting the leadership's goals," he said. "They found it difficult to accept this."

Here is the point: Even a 10% reduction in Chinese GDP would, in effect, zero out the overall growth of the economy.  Viewed this way, despite its role in the global economy, any "wealth creation" and growth in China may be accounted for entirely by the cost of degrading the local environment and increasing human disease and death.  You can understand how government officials might be uneasy about publicizing this figure.

According to officials at The World Bank, its "Cost of Pollution" report was similarly abridged for political reasons; "China's environmental agency insisted that the health statistics be removed from the published version of the report, citing the possible impact on 'social stability'."  As a result, one-third of the document was reportedly withheld from publication.  The tension between open communication and central control, and between development and damage, is evident in a press release from Gov.cn, the Government's official web site:

Even though the economic growth characterized by "high consumption, high pollution and high risk" is of its own historical significance in China, China's economy has been in the bottleneck period of resources and energy today and it cannot bear any risks of resources exhaustion.

Meanwhile, Chinese society has also entered the period with various conflicts protruding in which per capita GDP is about 1,000-3,000 US dollars, which cannot bear up any social problems caused by environmental pollution.

The government is clearly aware of the social and economic threats of environmental damage.  As reported by the Shanghai Daily, the most recent five year plan; "Requires energy consumption per unit of GDP to decline by 20 percent from the previous planning period.  The total amount of major pollutants discharged will be reduced by 10 percent, and forest coverage will be raised from 18.2 percent to 20 percent."

In an effort better address environmental concerns, in March of 2008 the State Council upgraded SEPA to a full Cabinet-level ministry.  To gather, "Accurate and high-quality data [of] pollution sources," the government launched in the first pollution census in February 2008.  And yet even while the central government attempts to close illegal and polluting coal mines and coal burning plants, journalists regularly report that local and regional authorities either ignore or explicitly condone the reopening of those facilities (1, 2, 3).

It does not appear that China's reliance on coal is going to decrease any time soon.  China has recently been building coal-fired plants at the rate of one every 7 to 10 days, with plans to build 500 more over the next decade.  The fraction of newly built power plants that burn coal has increased from 70% to 90% since 2000.  Thus, without either a more unified approach to reducing pollution or a substantially stronger response to that end by the central government, environmental damage will continue to directly plague both the economy and human health.

The Future Cost of the Building Boom

Here is something I don't see discussed in the press: where are the Chinese going to get all the coal to fire all the new power plants, especially when they are already facing supply shortfalls?  (Update: To clarify, I am less concerned here with the amount of coal in the ground than supply chain issues.  If they are already having trouble moving coal quickly enough to existing plants, how will they manage the increased demand?)  And while they may have the coal in the ground, how much will it cost to mine it with labor costs rising all across the country? And what about the costs of additional transportation infrastructure?

This brings us back to my father-in-law, sweltering away in Xiamen, and one of stumbling blocks the Chinese may be literally building for themselves.  As reported by The New York Times:

Each year for the past few years, China has built about 7.5 billion square feet of commercial and residential space, more than the combined floor space of all the malls and strip malls in the United States, according to data collected by the United States Energy Information Administration.

Chinese buildings rarely have thermal insulation. They require, on average, twice as much energy to heat and cool as those in similar climates in the United States and Europe, according to the World Bank. A vast majority of new buildings -- 95 percent, the bank says -- do not meet China's own codes for energy efficiency.

All these new buildings require China to build power plants, which it has been doing prodigiously. In 2005 alone, China added 66 gigawatts of electricity to its power grid, about as much power as Britain generates in a year. Last year, it added an additional 102 gigawatts, as much as France.

Damn.  So not only is China building enormous power generation capacity, but their underlying infrastructure is inherently inefficient.  This kind of systemic inefficiency is often attributed to, excused, or even just written off as a characteristic of a particular "stage of economic development" (see Keidel for one example).  It is certainly true that the U.S., Japan, and Europe all went through periods when the focus was on generating jobs and building wealth, only later to be followed up by mining inefficiencies to squeeze more product out of each unit of water and energy.

But all of China's infrastructure, all that housing and commercial space, is brand new.  So here are more questions: Is the government's plan to replace inefficient buildings over the next couple of decades?  Will labor remain so inexpensive that Chinese infrastructure is, in effect, disposable?  What are the secondary costs of maintaining that construction boom (e.g., energy, pollution, materials)?

It would seem that without a truly radical change in energy production, China is setting itself up to rely on dirty coal for many decades to come.  And so I wonder: How it is that the country will escape continued environmental damage that is equivalent to China's GDP growth?  You can't put off dealing with those costs forever.

The U.S. is borrowing cash from China to buy petroleum, and we have to sort that out as soon as possible.  But the Chinese are using their health, and thus their future productivity, as collateral for present growth. Even if they don't stumble, they may have to pause to catch their breath.

Ineffective Export Controls for US Technology

In the context of my ongoing skepticism about the effectiveness of regulation for improving biosecurity, here is a quick note on the utility of export controls for restricting transfer of sensitive technology.

Over at Wired News, Noah Shachtman has a post pointing to an article in Mother Jones about all the US weapons that are winding up in the hands of Iran.  Re-sale by third parties seems to be the short answer, but read the article to get the full story.

DNA Synthesis "Learning Curve": Thoughts on the Future of Building Genes and Organisms

With experience comes skill and efficiency.  That is the theory behind "learning" or "experience curves", which I played around with last week for DNA sequencing.  As promised, here are a few thoughts on the future of DNA synthesis.  Playing around with the synthesis curves a bit seems to kick out a couple of quantitative metrics for technological change.

For everything below, clicking on a Figure launches a pop-up with a full sized .jpg.  The data come from my papers, the Bio-era "Genome Synthesis and Design Futures" report, and a couple of my blog posts over the last year.

carlson_DNA_synthesis_learning_curve_june_08.jpg
Figure 1.

The simplest application of a learning curve to DNA synthesis is to compare productivity with cost.  Figure 1 shows those curves for both oligo synthesis and gene synthesis (click on the figure for a larger pop-up).  These lines are generated by taking the ratios of fits to data (shown in the inset).  This is necessary due to the methodological annoyance that productivity and cost data do not overlap -- the fits allow comparison of trends even when data is missing from one set or another.  As before, 1) I am not really thrilled to rely on power law fits to a small number of points, and 2) the projections (dashed lines) are really just for the sake of asking "what if?".
 

What can we learn from the figure?  First, the two lines cover different periods of time.  Thus it isn't completely kosher to compare them directly.  But with that in mind, we come to the second point: even the simple cost data in the inset makes clear that the commercial cost of synthetic genes is rapidly approaching the cost of the constituent single-stranded oligos. This is the result of competition, and is almost certainly due to new technologies introduced by those competitors.

Assuming that commercial gene foundries are making money, the "Assembly Cost" is probably falling because of increased automation and other gains in efficiency.  But it can't fall to zero, and there will (probably?) always be some profit margin for genes over oligos.  I am not going to guess at how low the Assembly Cost can fall, and the projections are drawn in by hand just for illustration.

carlson_synth_organism_learning_curve_june_08.jpg

Figure 2.

It isn't clear that a couple of straight lines in Figure 1 teach us much about the future, except in pondering the shrinking margins of gene foundries.  But combining the productivity information with my "Longest Synthetic DNA" plot gives a little more to chew on.  Figure 2 is a ratio of a curve fitted to the longest published synthetic DNA (sDNA) to the productivity curve.

In what follows, remember that the green line is based on data.

First, the caveat: the fit to the longest sDNA is basically a hand hack.  On a semilog plot I fit a curve consisting of a logarithm and a power law (not shown).  That means the actual functional form (on the original data) is a linear term plus a super power law in which the exponent increases with time.  There isn't any rationale for this function other than it fits the crazy data (in the inset), and I would be oh-so-wary of inferring anything deep from it.  Perhaps one could make the somewhat trivial observation that for a long time synthesizing DNA was hard (the linear regime), and then we entered a period when it has become progressively easier (the super power law).  I should probably win a prize for that.  No?  A lollipop?

There are a couple of interesting things about this curve, along which distance represents "progress".  First, so far as I am aware, commercial oligo synthesis started in 1992 and commercial gene foundries starting showing up in 1999.  The distance along the curve in those seven years is quite short, while the distance over the next nine years to the Venter Institute's recent synthetic chromosome is substantially larger.

This change in distance/speed represents some sort of quantitative measure of accelerating progress in synthesizing genomes, though frankly I am not yet settled on what the proper metric should be.  That is, how exactly should one measure distance or speed along this curve?  And then, given proper caution about the utility of the underlying fits to data, how seriously should one trust the metric?  Maybe it is just fine as is.  I am still pondering this.

Next, while the "learning curve" is presently "concave up", it really ought to turn over and level off sometime soon.  As I argued in the post on the Venter Institute's fine technical achievement, they are already well beyond what will be economically interesting for the foreseeable future, which is probably only 10-50 kilobases (kB).  It isn't at all clear that assembling sDNA larger than 100 kB will be anything more than an academic demonstration.  The red octagon (hint!) is positioned at about 100 MB, which is in the range of a human chromosome.  Even assembling something that large, and then using it to fabricate an artificial human chromosome, is probably not technologically that useful.  I reserve a bit of judgement here in the event it turns out that actually building functioning human chromosomes from smaller pieces is problematic.  But really, why bother otherwise?

carlson_longest_sDNA_vs_gene_cost_june_08.jpg
Figure 3.

Next, with the other curves in hand I couldn't help but compare the longest sDNA to gene assembly cost (beware the products of actual free time!).  (Update: Can't recall what I meant by this next sentence, so I struck it out.) Figure 3 may only be interesting because of what it doesn't show.  Note the reversed axis -- cost decreases to the right.

The assembly cost (inset) was generated simply by subtracting the oligo cost curve from the gene cost curve (see Figure 1 above) -- yes, I ignored the fact that those data are over different time periods.  There is no cost information available for any of the longest sDNA data, which all come from academic papers.  But the fact that gene assembly cost has been consistently halving every 18 months or so just serves to emphasize that the "acceleration" in the ratio of sDNA to assembly cost results from real improvements in processes and automation used to fabricate long sDNA.  I don't know that this is that deep an observation, but it does go some way towards providing additional quantitative estimates of progress in developing biological technologies.